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fluoxetine increases toxicity of amifampridine by Other (see comment). Modify Therapy/Monitor Closely. Comment: Amifampridine can cause seizures. Coadministration with drugs that lower seizure threshold may increase this risk. amiodarone. amiodarone will increase the level or effect of fluoxetine by affecting hepatic enzyme CYP2D6 metabolism. Large overdoses of fluoxetine may cause seizures. Other signs of an overdose may include lethargy, agitation, incoordination, and excess kaitlib coupon Antidepressants can increase the risk of suicidal thinking and behavior in children, adolescents, and young adults with major depressive disorder. Antidepressants (often SSRIs) can cause hyponatraemia and seizures may occur where this is severe. Consider the need for neurologist input

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(Advil, Motrin), or a combination of acetaminophen, aspirin, and caffeine (Excedrin Migraine) can sometimes help ease migraine headaches.

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